Digestive Disease Research Development Center
C-TREAT - Center for Tissue Repair, Epithelial Biology and Inflammation, And Transformation

C-TREAT's Goals

News

Spotlight

Congratuations to Declan McCole,Ph.D.!!!!

Dr. McCole will receive one of the first new grants under the Biomedical Research on the International Space Station (BioMed-ISS) initiative. It's a collaborative effort between NIH and NASA.

Dr. McCole's research will look at excessive alcohol use, which is a leading lifestyle-relate cause of death in the US. A major factor in alcohol-related disease stems from the ability of alcohol to compromise the natural barrier function of cells in the GI tract, increasing the movement of toxins from the intestine to other organs of the body. Using microgravity 3-D cell culture models, he plans to study the barrier properties of the intestines and to explore how the absence of gravity affects alcohol's ability to diminish the barrier.